Journal of Environmental and Public Health / 2016 / Article / Tab 1

Research Article

The LINA Study: Higher Sensitivity of Infant Compared to Maternal Eosinophil/Basophil Progenitors to Indoor Chemical Exposures

Table 1

Characteristics of the analysed subcohort and the remaining LINA cohort. (A) General characteristics assessed during the 36th week of pregnancy. (B) Indoor chemical exposures during the second year of life. (C) Infant’s respiratory outcomes during the second year of life.

ParametersAnalysed subcohort
(%),
Remaining cohort
(%),
value

(A) General characteristics
Month of birth
  Nov–Feb16 (23.5)140 (29.3)0.502
  Mar-Apr, Sept-Oct28 (41.2)162 (33.9)
  May–Aug24 (35.3)176 (36.8)
Gender of the child
  Female29 (42.6)235 (49.2)0.349
  Male39 (57.4)243 (50.8)
Parental education
  Low0 (0)6 (1.3)0.294
  Intermediate19 (27.9)101 (21.1)
  High49 (72.1)371 (77.6)
Family history of atopy
  Double positive18 (26.5)80 (16.7)0.167
  Single positive26 (38.2)234 (49.0)
  Negative24 (35.3)164 (34.3)
Exposure to ETS in dwelling during pregnancy
  Yes11 (16.2)59 (12.3)0.430
  No57 (83.8)419 (87.7)
 Dampness in dwelling during the second year of life
  Yes6 (9.2)46 (10.9)0.700
  No59 (90.2)377 (89.1)

(B) Indoor chemical exposure during the second year of life
Exposure to ETS in dwelling
  Yes7 (10.4)27 (5.7)0.222
  No60 (89.6)445 (94.3)
Number of smoked cigarettes/day in dwelling
  ≥153 (4.5)7 (1.5)0.173
  1–144 (6.0)10 (2.2)
  060 (89.5)447 (96.3)
  Usage of disinfectants
  Yes40 (61.5)294 (65.0)0.608
  No25 (38.5)158 (35.0)

(C) Respiratory outcomes during second year of life
Wheezing ever
  Positive15 (22.7)101 (21.8)0.878
  Negative51 (77.3)362 (78.2)
Recurrent wheezing
  Positive12 (19.0)54 (12.5)0.207
  Negative51 (81.0)377 (87.5)
Wheezing requiring medical treatment
  Positive 7 (10.3)26 (5.7)0.231
  Negative61 (89.7)432 (94.3)
Bronchitis
  Positive18 (28.6)125 (27.7)0.887
  Negative45 (71.4)326 (72.3)
Obstructive bronchitis
  Positive6 (9.4)42 (9.6)0.962
  Negative58 (90.6)396 (90.4)

may be different from 68 due to missing data.
may be different from 478 due to missing data.
Calculated using the chi squared test for cross relationship.
Low = 9 yrs of schooling or less “Hauptschulabschluss”; intermediate = 10 yrs of schooling “Mittlere Reife”; high = 12 yrs of schooling or more “(Fach-)hochschulreife.”
Family history of atopy is defined as occurrence of asthma, atopic dermatitis, hay fever, or food allergy.
Yes = (almost) daily, once a week or more, or occasionally; no = never.
Calculated although numbers are <5 in some subgroups.

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