Journal of Environmental and Public Health / 2018 / Article / Tab 1

Research Article

Assessing Cancer Risk Associated with Aquatic Polycyclic Aromatic Hydrocarbon Pollution Reveals Dietary Routes of Exposure and Vulnerable Populations

Table 1

Monte Carlo simulation variables and distributions for cancer risk assessment due to oral and dermal sediment exposure at the AWI Superfund site.

ParameterSymbolUnitsDistribution-ATDistribution-CTDistribution-ARDistribution-CR

Concentration of 7 PAHs in sedimentCSmg/kg0.2830.2830.2830.283
Average time-CancerATdays25550255502555025550
Age-dependent adjustment factorADAFUnitless110110
Conversion factorCFUnitless0.0000010.0000010.0000010.000001
Body weightBWkg80 ± 2015 ± 3.7580 ± 2015 ± 3.75

Oral exposure
Benzo(a)anthracene cancer slope factorBaAmg/kg-day7.30E − 017.30E − 017.30E − 017.30E − 01
Benzo(a)pyrene cancer slope factorBaPmg/kg-day7.30E + 007.30E + 007.30E + 007.30E + 00
Benzo(b)fluoranthene cancer slope factorBbFmg/kg-day7.30E − 017.30E − 017.30E − 017.30E − 01
Benzo(k)fluoranthene cancer slope factorBkFmg/kg-day7.30E − 027.30E − 027.30E − 027.30E − 02
Chrysene cancer slope factorChrmg/kg-day7.30E − 037.30E − 037.30E − 037.30E − 03
Dibenz(a,h)anthracene cancer slope factorDibmg/kg-day7.30E + 007.30E + 007.30E + 007.30E + 00
Indeno(1,2,3-c,d)pyrene cancer slope factorIndmg/kg-day7.30E − 017.30E − 017.30E − 017.30E − 01
Exposure frequencyEFdays/year40 ± 1052 ± 1332 ± 848 ± 12
Exposure durationEDyears20 ± 56 ± 1.520 ± 56 ± 1.5
Ingestion rate-sedimentIR-Smg/day20 ± 550 ± 12.520 ± 550 ± 12.5

Dermal exposure
Benzo(a)anthracene cancer slope factorBaAmg/kg-day2.50E + 002.50E + 002.50E + 002.50E + 00
Benzo(a)pyrene cancer slope factorBaPmg/kg-day2.50E + 012.50E + 012.50E + 012.50E + 01
Benzo(b)fluoranthene cancer slope factorBbFmg/kg-day2.50E + 002.50E + 002.50E + 002.50E + 00
Benzo(k)fluoranthene cancer slope factorBkFmg/kg-day2.50E − 012.50E − 012.50E − 012.50E − 01
Chrysene cancer slope factorChrmg/kg-day2.50E − 022.50E − 022.50E − 022.50E − 02
Dibenz(a,h)anthracene cancer slope factorDibmg/kg-day2.50E + 012.50E + 012.50E + 012.50E + 01
Indeno(1,2,3-c,d)pyrene cancer slope factorIndmg/kg-day2.50E + 002.50E + 002.50E + 002.50E + 00
Exposure frequencyEFdays/year40 ± 1052 ± 1332 ± 848 ± 12
Exposure durationEDyears20 ± 56 ± 1.520 ± 56 ± 1.5
Soil to skin adherence factorAFmg/cm2-day0.07 ± 0.01750.2 ± 0.050.2 ± 0.050.07 ± 0.0175
Dermal absorption fractionABSdUnitless0.130.130.130.13
Skin surface area available for contactSAcm26032 ± 15082373 ± 593.256032 ± 15082373 ± 593.25

AT = adult trespasser; CT = child trespasser; AR = adult recreational user; CR = child recreational user.

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