Research Article

Reasons for Declining Consent in a Population-Based Cohort Study Conducted in a Rural South American Community

Table 2

Procedures and diagnostic tests performed in the population enrolled in the Atahualpa Project cohort and main reasons for refusal.

Diagnostic testNumber (characteristics) of invited individualsNumber (%) of acceptanceMain reasons for refusal

Blood test (year 2013)616 (aged ≥40 years)517 (84)Fear of the needle.
Time constraints
Blood test (year 2014)267 (aged ≥60 years)220 (82)
Blood test (year 2015)351 (aged ≥60 years)259 (74)
Blood test (year 2016)351 (aged ≥60 years)319 (90)
Computed tomography817 (aged ≥40 years)701 (86)Time constraints
Fear of travel
Magnetic resonance480 (aged ≥60 years)§446 (93)
Ankle-brachial index475 (aged ≥60 years)§382 (80)Time constraints
Lack of interest
Carotid ultrasounds691 (aged ≥40 years)594 (86)
Abdominal ultrasounds358 (aged ≥40 years)277 (77)
Transcranial Doppler90 (aged ≥60 years)73 (81)
Electroencephalograms180 (aged ≥40 years)163 (91)
Polysomnography172 (aged ≥40 years)144 (84)Don’t want to sleep out
24-hour Holter monitoring315 (aged ≥60 years)273 (87)Don’t want to carry the device for 24 hours
Aortic carotid stiffness330 (aged ≥60 years)300 (90)Time constraints
Lack of interest
Community lectures (2013)327 (aged ≥60 years)228 (70)Time constraints
Lack of interest
Community lectures (2015)349 (aged ≥60 years)208 (60)
Community lectures (2017)338 (aged ≥60 years)¥312 (92)

Exams performed over different study years. §Invitations also extended to certain individuals aged 40–59 years presenting with specific disorders of interest. Invitations extended to certain individuals according to study design (not population based). ¥Visual acuity determinations and prescription glasses offered to attendants.