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Journal of Environmental and Public Health
Volume 2018, Article ID 8565498, 6 pages
Research Article

Assessment of Quality of Life among Children with End-Stage Renal Disease: A Cross-Sectional Study

1Department of Public Health and Community Medicine, Faculty of Medicine, Cairo University, Giza, Egypt
2Department of Pediatrics Medicine, Faculty of Medicine, Cairo University, Giza, Egypt

Correspondence should be addressed to Arwa M. El Shafei; ge.ude.ynialarsak@iefahsawra

Received 12 March 2018; Revised 12 July 2018; Accepted 31 July 2018; Published 16 September 2018

Academic Editor: Csaba Siffel

Copyright © 2018 Arwa M. El Shafei et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Measuring health-related quality of life is considered an important outcome indicator in evaluating health-care interventions and treatments and in understanding the burden of diseases. Objectives. This study aimed at assessing quality of life among children with end-stage renal disease, either undergoing hemodialysis or had renal transplantation therapy and comparing it with healthy controls. Methods. A cross-sectional study was conducted between December 2016 and May 2017 in Abo El-Reesh Pediatric Hospital using parent/child reports of generic module for QoL assessment: PedsQLTM Inventory version 4 for both cases and controls. Disease-specific module: PedsQLTM ESRD version 3 was used for ESRD cases. 55 ESRD cases and 86 controls were enrolled in the study. Results. Statistically significant difference between ESRD cases and controls regarding all aspects of QoL was found; total QoL mean score was 58.4 ± 15.3 and 86.8 ± 10 among cases and controls, respectively. All individual QoL domains were significantly worse in ESRD cases. Transplantation group had better Spearman’s correlation between child and parents’ scores which showed significant positive moderate correlation. Conclusions. ESRD and its treatment modalities are affecting negatively all aspects of quality of life; incorporating QoL assessment and management is highly recommended.