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Journal of Food Quality
Volume 2017 (2017), Article ID 7636237, 10 pages
Research Article

Antioxidant and Cytotoxicological Effects of Aloe vera Food Supplements

1Cell Biology Laboratory, Centro Universitario de la Ciénega, Universidad de Guadalajara, Av. Universidad 1115, 47810 Ocotlán, JAL, Mexico
2Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Boulevard del Maestro s/n, 88710 Reynosa, TAMPS, Mexico
3Centro de Excelencia, Universidad Autónoma de Tamaulipas, Matamoros s/n, 87000 Cd. Victoria, TAMPS, Mexico

Correspondence should be addressed to Peter Knauth

Received 25 November 2016; Revised 24 January 2017; Accepted 15 February 2017; Published 7 March 2017

Academic Editor: Giuseppe Zeppa

Copyright © 2017 Zaira López et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Currently, food industries use supplements from Aloe vera as highly concentrated powders (starting products), which are added to the final product at a concentration of 1x, meaning 10 g/L for decolourized and spray-dried whole leaf powder (WLP) or 5 g/L for decolourized and spray-dried inner leaf powder (ILG) and also for nondecolourized and belt-dried inner leaf powder (ILF). Flavonoids, tannins, or saponins could not be detected for any starting product at this concentration and their total phenol concentration of 68–112 μM gallate-eq. was much lower than in fresh extract; however, their antioxidant capacity of 90–123 μM ascorbate-eq. for DPPH was similar to the fresh extract. Starting products, dissolved at 1x, had an aloin concentration of 0.04 to 0.07 ppm, a concentration much lower than the industry standard of 10 ppm for foodstuff. While decolourized starting products (i.e., treated with activated carbon) exhibited low cytotoxicity on HeLa cells (CC50 = 15 g/L ILG or 50 g/L WLP), ILF at CC50 = 1–5 g/L exhibited cytotoxic effects, that is, at concentrations even below the recommended for human consumption. Probable causes for the cytotoxicity of ILF are the exposure to high temperatures (70–85°C) combined with a high fibre content.