Extraction of Flavonoids from Corn Silk and Biological Activities In Vitro

Table 2

The advantages and disadvantages of various extraction methods.

Extraction methods	Advantages	Disadvantages
Ethanol reflux extraction	Less dosage, short extraction time, less impurities, complete extraction	Volatile and toxic
Aqueous extraction	Simple operation, low cost, suitable for large-scale production	More impurities
Microwave-assisted extraction	High selectivity, fast and efficient, stable quality	The extraction time is too long and the temperature is too high, but the extraction rate decreases
Ultrasonic-assisted extraction	Short extraction time and high yield without heating	Small extraction scale, not suitable for large-scale production
Supercritical fluid extraction	Low extraction temperature, high extraction rate, low solvent consumption, no pollution	The separation selectivity is reduced, it is not easy to obtain a pure substance, the investment is large, and the operating component is high