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| Reference | Application of Blockchain | Type of Blockchain used | Advantages | Limitations | Simulation parameters used | Future work |
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| [61] | Managing medical records and other data | Private and public Blockchain | To reduce the various attacks, such as DOS, modification of data, mining attack and storage attack, in the healthcare system | Blockchain technology is resource-constrained, so it is not suitable for many IoT devices. There are some more issues in Blockchain technology-related costs; it requires high bandwidth and more computational power | — | To explore more security issues, and implementation is done to provide some real work |
| [40] | Patient Monitoring/Electronic Health Record (ERH) | | Blockchain integrated with IoT overcomes the security issues that are faced by healthcare applications | Many issues are not considered yet such as mining incentives, and there are some specific Blockchain attacks, which halt the entire system | — | |
| [43] | Drug traceability | | To overcome the issue of privacy and authentication of data, increase the flexibility of the system | The drug traceability scenario, which is shown in this paper, is complex | Traceability data authenticity and privacy | To make the system more prone to DoS attacks while comparing with the traditional system |
| [44] | Drug traceability | Public Blockchain | The integration of IoT with Blockchain makes the drug supply chain system more secure and reliable and avoids any drug fraud by tracking each drug in the supply chain | Implementation is not done | Privacy, limiting theft and diversion | |
| [45] | Drug traceability | — | Improves the efficiency of data exchange | — | Information infrastructure breakdown, information delays, and transparency of drug supply chain | Analysis of the regulatory impact and system simulation test is done in the future |
| [46] | Drug traceability | — | Detects fake medicines in of supply chain | The consumption of unauthorized and Ingenium medicines not to be eliminated in this system | Resistance against single point of failure, counterfeit medicine detection, diverted medicine detection, medicine shortage detection, ease of operations, involvement of stakeholders, transparency, privacy, security, immutability | This particular framework can be implemented in many domains like courier consignment tracking, election management |
| [53] | Patient Monitoring/Electronic Health Record (ERH) | Private Blockchain | The system secures the data and uses the patient’s data in a more relevant form | Time is the main aspect, but there is some delay while verifying each block in the Blockchain. Maintaining the security of each node is also the main challenge | Speed, privacy, transparency, traceability, availability, confidentiality | Implementation is done using the Ethereum Blockchain; to explore more implementation parts use hyperledger |
| [59] | Managing medical records and other data | Public | It ensures the patient that any illegal activity cannot be done. It focuses on the transparency of records and the security of data | Transaction time is a very important aspect of healthcare applications. This framework does not focus on transaction time | Number of nodes in a CRN, grid facet, transmission range data size or users request, simulation time | This framework experiments with the illegal activities done on IoT devices but does not experiment with the cost required during the communication. So, in the future experiment on the cost required in communication is to be done |
| [62] | Managing medical records and other data | Public | The interoperability trust model for healthcare IoT | Identification of patterns of symptoms, which are obtained from wearable devices cannot be done | Scalability, data integrity, mutual authentication, trustworthiness, privacy | Artificial intelligence and deep learning technology are used in training states to authenticate and identify the pattern to enhance the framework |
| [60] | Managing medical records and other data | Variation of the Blockchain is used in personal health care and external Blockchain for record management | An uplifting of society with accurate and efficient healthcare | Implementation is not done | — | To implement the framework and to check whether the framework is secure or not |
| [54] | Patient Monitoring/Electronic Health Record (ERH) | Cannot prefer any particular Blockchain | Try to remove the obstacles and give a more secure network | Implementation is not done | — | To test the performance of the framework, implementation is necessary in the future |
| [57] | Managing medical records and other data | Medical devices Blockchain consultation Blockchain | Paper works on the security issues | It cannot cover all the security aspects of IoT. It cannot consider the attacks in IoT | — | To make a more secure framework of health monitoring, this proposed framework has to implement more functionality based on attacks |
| [51] | Patient Monitoring/Electronic Health Record (ERH) | Public Blockchain | Healthcare devices that read the vital signs of patients and share that information with the authorized doctors and hospitals in a secure Blockchain network | Lack of communication between the server and devices | Energy consumption and efficiency | Interoperability is also an essential aspect of the healthcare system to check the interoperability performance of the system with different IoT frameworks |
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