Journal of Food Quality / 2021 / Article / Tab 1

Research Article

Inhibitory Effects of Myricetrin and Dihydromyricetin toward α-Glucosidase and Pancreatic Lipase with Molecular Docking Analyses and Their Interaction

Table 1

Interaction between myricetrin and dihydromyricetin on α-glucosidase inhibition.

RatioMyricetrinDihydromyricetinα-Glucosidase inhibition (%)CIaFab (%)CI for FaMyricetrinDihydromyricetin
Tested concentration (μg/mL)Calculated concentration (μg/mL)

1 : 112.512.512.80 ± 1.531.31325.01.23619.5819.58
25.025.033.40 ± 1.511.22550.01.10134.4534.45
37.537.552.48 ± 1.941.12775.00.98360.6160.61
50.050.068.42 ± 1.440.99290.00.880106.64106.64
62.562.576.68 ± 0.620.958

1 : 28.316.716.80 ± 2.190.82125.00.82511.4722.94
16.733.337.34 ± 2.270.83150.00.87524.3848.76
25.050.052.10 ± 2.540.85175.00.93251.84103.68
33.366.760.54 ± 2.010.91390.00.996110.22220.44
41.683.468.07 ± 2.670.929

2 : 116.78.344.26 ± 3.360.57725.00.4387.463.73
33.316.754.62 ± 1.100.89250.00.72724.2212.11
50.025.062.19 ± 1.031.10775.01.20778.6639.33
66.733.372.47 ± 1.171.10990.02.007255.28127.64
83.341.778.61 ± 3.921.130

aCI, combination index. CI ≤ 0.90, 0.90 < CI < 1.10, and CI ≥ 1.10 indicate synergistic, additive, and antagonistic effects, respectively; bFa, fraction affected by the combination dose of myricetrin and dihydromyricetin.

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