In Vivo Diffuse Optical Tomography and Fluorescence Molecular Tomography

Li, Mingze; Zhang, Yonghong; Bai, Jing

doi:https://doi.org/10.1260/2040-2295.1.3.477

Journal of Healthcare Engineering

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Research Article | Open Access

Volume 1 | Article ID 279745 | https://doi.org/10.1260/2040-2295.1.3.477

In Vivo Diffuse Optical Tomography and Fluorescence Molecular Tomography

Mingze Li,¹Yonghong Zhang,¹and Jing Bai¹

Abstract

Diffuse optical tomography (DOT) and fluorescence molecular tomography (FMT) are two attractive imaging techniques for in vivo physiological and psychological research. They have distinct advantages such as non-invasiveness, non-ionizing radiation, high sensitivity and longitudinal monitoring. This paper reviews the key components of DOT and FMT. Light propagation model, mathematical reconstruction algorithm, imaging instrumentation and medical applications are included. Future challenges and perspective on optical tomography are discussed.

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