Microencapsulating and Banking Living Cells for Cell-Based Medicine

Zhang, Wujie; He, Xiaoming

doi:https://doi.org/10.1260/2040-2295.2.4.427

Journal of Healthcare Engineering

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Research Article | Open Access

Volume 2 | Article ID 875406 | https://doi.org/10.1260/2040-2295.2.4.427

Microencapsulating and Banking Living Cells for Cell-Based Medicine

Wujie Zhang^1,2and Xiaoming He^1,2,3

Received01 Mar 2011

Accepted01 Aug 2011

Abstract

A major challenge to the eventual success of the emerging cell-based medicine such as tissue engineering, regenerative medicine, and cell transplantation is the limited availability of the desired cell sources. This challenge can be addressed by cell microencapsulation to overcome the undesired immune response (i.e., to achieve immunoisolation) so that non-autologous cells can be used to treat human diseases, and by cell/tissue preservation to bank living cells for wide distribution to end users so that they are readily available when needed in the future. This review summarizes the status quo of research in both cell microencapsulation and banking the microencapsulated cells. It is concluded with a brief outlook of future research directions in this important field.

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