Table of Contents Author Guidelines Submit a Manuscript
Journal of Healthcare Engineering
Volume 4, Issue 3, Pages 329-370
http://dx.doi.org/10.1260/2040-2295.4.3.329
Research Article

Bioreactors as Engineering Support to Treat Cardiac Muscle and Vascular Disease

Diana Massai, Giulia Cerino, Diego Gallo, Francesco Pennella, Marco A. Deriu, Andres Rodriguez, Franco M. Montevecchi, Cristina Bignardi, Alberto Audenino, and Umberto Morbiducci

Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy

Received 1 November 2012; Accepted 1 March 2013

Copyright © 2013 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [16 citations]

The following is the list of published articles that have cited the current article.

  • Maximilian Y. Emmert, Robert W. Hitchcock, and Simon P. Hoerstrup, “Cell therapy, 3D culture systems and tissue engineering for cardiac regeneration,” Advanced Drug Delivery Reviews, 2013. View at Publisher · View at Google Scholar
  • Julia Schulte, Anja Friedrich, Trixi Hollweck, Fabian König, Markus Eblenkamp, Andres Beiras-Fernandez, Cornelia Fano, Christian Hagl, and Bassil Akra, “A Novel Seeding and Conditioning Bioreactor for Vascular Tissue Engineering,” Processes, vol. 2, no. 3, pp. 526–547, 2014. View at Publisher · View at Google Scholar
  • D. A. Taylor, L. C. Sampaio, and A. Gobin, “Building New Hearts: A Review of Trends in Cardiac Tissue Engineering,” American Journal of Transplantation, vol. 14, no. 11, pp. 2448–2459, 2014. View at Publisher · View at Google Scholar
  • Giulia Cerino, Emanuele Gaudiello, Thomas Grussenmeyer, Ludovic Melly, Diana Massai, Andrea Banfi, Ivan Martin, Friedrich Eckstein, Martin Grapow, and Anna Marsano, “Three dimensional multi-cellular muscle-like tissue engineering in perfusion-based bioreactors,” Biotechnology and Bioengineering, 2015. View at Publisher · View at Google Scholar
  • Whitney L. Stoppel, David L. Kaplan, and Lauren D. Black, “Electrical and Mechanical Stimulation of Cardiac Cells and Tissue Constructs,” Advanced Drug Delivery Reviews, 2015. View at Publisher · View at Google Scholar
  • Andrew Trumbull, Gayathri Subramanian, and Eda Yildirim-Ayan, “Mechanoresponsive musculoskeletal tissue differentiation of adipose-derived stem cells,” BioMedical Engineering OnLine, vol. 15, no. 1, 2016. View at Publisher · View at Google Scholar
  • Ulrike Ritz, Peter Kögler, Isabel Höfer, Petra Frank, Sven Klees, Sören Gebhard, Christian Brendel, Kerstin Kaufmann, Alexander Hofmann, Pol Maria Rommens, and Ulrich Jonas, “Photocrosslinkable polysaccharide hydrogel composites based on dextran or pullulan–amylose blends with cytokines for a human co-culture model of human osteoblasts and endothelial cells,” J. Mater. Chem. B, 2016. View at Publisher · View at Google Scholar
  • Ji Hyun Kim, and James J. Yoo, “Current Developments and Future Perspectives of Tissue Engineering and Regenerative Medicine,” Clinical Regenerative Medicine in Urology, pp. 3–14, 2017. View at Publisher · View at Google Scholar
  • V. I. Sevastianov, Yu. B. Basok, A. M. Grigoryev, L. A. Kirsanova, and V. N. Vasilets, “A Perfusion Bioreactor for Making Tissue-Engineered Constructs,” Biomedical Engineering, 2017. View at Publisher · View at Google Scholar
  • Silvia Caddeo, Monica Boffito, and Susanna Sartori, “Tissue Engineering Approaches in the Design of Healthy and Pathological In Vitro Tissue Models,” Frontiers in Bioengineering and Biotechnology, vol. 5, 2017. View at Publisher · View at Google Scholar
  • Diana Massai, Emiliano Bolesani, Diana Robles Diaz, Christina Kropp, Henning Kempf, Caroline Halloin, Ulrich Martin, Tudor Braniste, Giuseppe Isu, Vanessa Harms, Umberto Morbiducci, Gerald Dräger, and Robert Zweigerdt, “Sensitivity of human pluripotent stem cells to insulin precipitation induced by peristaltic pump-based medium circulation: considerations on process development,” Scientific Reports, vol. 7, no. 1, 2017. View at Publisher · View at Google Scholar
  • Raquel Obregón, Javier Ramón-Azcón, and Samad Ahadian, “Bioreactors in Tissue Engineering,” Tissue Engineering for Artificial Organs, pp. 169–213, 2017. View at Publisher · View at Google Scholar
  • Isotta Chimenti, Diana Massai, Umberto Morbiducci, Antonio Paolo Beltrami, Maurizio Pesce, and Elisa Messina, “Stem Cell Spheroids and Ex Vivo Niche Modeling: Rationalization and Scaling-Up,” Journal of Cardiovascular Translational Research, 2017. View at Publisher · View at Google Scholar
  • Leila Mohammadi Amirabad, Mohammad Massumi, Mehdi Shamsara, Iman Shabani, Afshin Amari, Majid Mossahebi Mohammadi, Simzar Hosseinzadeh, Saeid Vakilian, Sarah K. Steinbach, Mohammad Reza Khorramizadeh, Masoud Soleimani, and Jalal Barzin, “Enhanced cardiac differentiation of human CVD patient-specific iPS cells by applying unidirectional electrical pulses using aligned electroactive nanofibrous scaffolds,” ACS Applied Materials & Interfaces, 2017. View at Publisher · View at Google Scholar
  • Yun-Xiang Zhang, Ting-Ting Yang, Liu Xia, Wei-Fen Zhang, Jia-Fu Wang, and Ya-Ping Wu, “Inhibitory Effect of Propolis on Platelet Aggregation In Vitro,” Journal of Healthcare Engineering, vol. 2017, pp. 1–6, 2017. View at Publisher · View at Google Scholar
  • Gianvito Grasso, Stefano Muscat, Martina Rebella, Umberto Morbiducci, Alberto Audenino, Andrea Danani, and Marco A. Deriu, “Cell Penetrating Peptide Modulation of Membrane Biomechanics by Molecular Dynamics,” Journal of Biomechanics, 2018. View at Publisher · View at Google Scholar