Journal of Healthcare Engineering

Journal of Healthcare Engineering / 2015 / Article

Research Article | Open Access

Volume 6 |Article ID 627464 | 12 pages | https://doi.org/10.1260/2040-2295.6.4.705

Development and Evaluation of an Automated, Home-Based, Electronic Questionnaire for Detecting COPD Exacerbations

Received01 Apr 2015
Accepted01 Sep 2015

Abstract

Collaboration between patients and their medical and technical experts enabled the development of an automated questionnaire for the early detection of COPD exacerbations (AQCE). The questionnaire consisted of fourteen questions and was implemented on a computer system for use by patients at home in an un-supervised environment. Psychometric evaluation was conducted after a 6-month field trial. Fifty-two patients were involved in the development of the questionnaire. Reproducibility was studied using 19 patients (ICC = 0.94). Sixteen out of the 19 subjects started the 6 month-field trial with the computer application. Cronbach’s alpha of 0.81 was achieved. In the concurrent validity analysis, a correlation of 0.80 (p = 0.002) with the CCQ was reported. The results suggest that AQCE is a valid and reliable questionnaire, showing that an automated home-based electronic questionnaire may enable early detection of exacerbations of COPD.

References

  1. A. Anzueto, “Impact of exacerbations on COPD,” Eur Respir Rev., vol. 19, no. 116, pp. 113–118, 2010. View at: Google Scholar
  2. A. J. Mackay and J. R. Hurst, “COPD Exacerbations: Causes, Prevention, and Treatment,” Immunol Allergy Clin N Am., vol. 33, pp. 95–115, 2013. View at: Google Scholar
  3. J. A. Wedzicha and G. C. Donaldson, “Exacerbations of Chronic Obstructive Pulmonary Disease,” Respir Care., vol. 48, pp. 1204–1213, 2003. View at: Google Scholar
  4. Global Strategy for the Diagnosis, Management and Prevention of COPD. Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2015. http://www.goldcopd.org/. Accessed March 29, 2015.
  5. T. A. Seemungal, G. C. Donaldson, E. A. Paul, J. C. Bestall, D. J. Jeffries, and J. A. Wedzicha, “Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease,” Am J Respir Crit Care Med., vol. 157, pp. 1418–1422, 1998. View at: Google Scholar
  6. G. C. Donaldson, T. A. R. Seemungal, A. Bhowmik, and J. A. Wedzicha, “Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease,” Thorax, vol. 57, pp. 847–852, 2002. View at: Google Scholar
  7. M. K. Pasquale, S. X. Sun, F. Song, H. J. Hartnett, and S. A. Stemkowski, “Impact of exacerbations on health care cost and resource utilization in chronic obstructive pulmonary disease patients with chronic bronchitis from a predominantly Medicare population,” Int J Chron Obstruct Pulmon Dis., vol. 7, pp. 757–764, 2012. View at: Google Scholar
  8. K. Vijayasaratha and R. A. Stockley, “Reported and unreported exacerbations of COPD: analysis by diary cards,” Chest, vol. 133, no. 1, pp. 34–41, 2008. View at: Google Scholar
  9. T. M. Wilkinson, G. C. Donaldson, J. R. Hurst, T. A. Seemungal, and J. A. Wedzicha, “Early therapy improves outcomes of exacerbations of chronic obstructive pulmonary disease,” Am J Respir Crit Care Med., vol. 169, no. 12, pp. 1298–1303, 2004. View at: Google Scholar
  10. N. K. Leidy, T. K. Wilcox, P. W. Jones et al., “Standardizing measurement of chronic obstructive pulmonary disease exacerbations. Reliability and validity of a patient-reported diary,” Am J Respir Crit Care Med., vol. 183, no. 3, pp. 323–329, 2011. View at: Google Scholar
  11. G. L. Snider, “Nosology for our day: its application to chronic obstructive pulmonary disease,” Am J Respir Crit Care Med., vol. 167, no. 5, pp. 678–683, 2003. View at: Google Scholar
  12. L. Langsetmo, R. W. Platt, P. Ernst, and J. Bourbeau, “Underreporting exacerbation of chronic obstructive pulmonary disease in a longitudinal cohort,” Am J Respir Crit Care Med., vol. 177, no. 4, pp. 396–401, 2008. View at: Google Scholar
  13. I. S. Woolhouse, S. L. Hill, and R. A. Stockley, “Symptom resolution assessed using a patient directed diary card during treatment of acute exacerbations of chronic bronchitis,” Thorax, vol. 56, no. 12, pp. 947–953, 2001. View at: Google Scholar
  14. D. S. Morillo, Crespo Mario, A. León, and L. F. Crespo, “A novel multimodal tool for telemonitoring patients with COPD,” Inform Health Soc Care, vol. 40, no. 1, pp. 1–22, 2015. View at: Google Scholar
  15. N. R. Anthonisen, J. Manfreda, C. P. W. Warren, E. S. Hershfield, G. K. M. Harding, and N. A. Nelson, “Antibiotic Therapy in Exacerbations of Chronic Obstructive Pulmonary Disease,” Ann Intern Med., vol. 106, no. 2, pp. 196–204, 1987. View at: Google Scholar
  16. T. van der Molen, B. W. M. Willemse, S. Shokker, N. H. T. Ten Hakken, D. S. Postma, and E. F. Juniper, “Development, validity and responsiveness of the clinical COPD questionnaire,” Health Qual Life Outcomes, vol. 1:13, 2003. View at: Google Scholar
  17. B. M. Aparacio, M. I. Vázquez, and V. H. Hernando, “Fiabilidad y validez de la versión espanola del Clinical COPD Questionnaire (CCQ),” Arch Bronconeumol., vol. 46:108s, 2010. View at: Google Scholar
  18. R. F. Pokrzywinsky, D. M. Meas, S. P. McKenna, A. L. Glendenning, and D. A. Revicki, “Development and psychometric assessment of the COPD and Asthma Sleep Impact Scale (CASIS),” Health Qual Life Outcomes, vol. 7:98, 2009. View at: Google Scholar
  19. R. Lahoz, J. Galera, M. Lleonart, and M. Miravitlles, Validation of the Spanish version of the “COPD and asthma sleep impact scale (CASIS)” questionnaire (PRS39, October 2009, ISPOR 12th Annual European Congress, Paris, France).
  20. C. B. Terwee, S. D. Bot, M. R. de Boer et al., “Quality criteria were proposed for measurement properties of health status questionnaires,” J Clin Epidemiol., vol. 60, no. 1, pp. 34–42, 2007. View at: Google Scholar
  21. J. C. Nunnally and I. H. Bernstein, Psychometric theory, McGraw-Hill, New York, 3rd edition, 1994.
  22. P. W. Jones, “Health status measurement in chronic obstructive pulmonary disease,” Thorax, vol. 56, no. 11, pp. 880–887, 2001. View at: Google Scholar
  23. M. Westwood, J. Bourbeau, P. W. Jones, A. Cerulli, G. Capkun-Niggli, and G. Worthy, “Relationship between FEV1 change and patient-reported outcomes in randomised trials of inhaled bronchodilators for stable COPD: a systematic review,” Respir Res., vol. 12:40, 2011. View at: Google Scholar
  24. B. R. Celli and J. Vestbo, “The EXACT-Pro: Measuring Exacerbations of COPD,” Am J Respir Crit Care Med., vol. 183, no. 3, pp. 287–288, 2011. View at: Google Scholar
  25. B. McKinstry, “The use of remote monitoring technologies in managing chronic obstructive pulmonary disease,” QJM, vol. 106, no. 10, pp. 883–885, 2013. View at: Google Scholar
  26. J. C. A. Trappenburg, I. Touwen, G. H. de Weert-van Oene et al., “Detecting exacerbations using the Clinical COPD Questionnaire,” Health Qual Life Outcomes, vol. 8:102, 2010. View at: Google Scholar
  27. A. J. Mackay, G. C. Donaldson, A. R. Patel, R. Singh, B. Kowlessar, and J. A. Wedzicha, “Detection and severity grading of COPD exacerbations using the Exacerbations of Chronic Obstructive Pulmonary Disease Tool (EXACT),” Eur Respir J., vol. 43, no. 3, pp. 735–744, 2014. View at: Google Scholar
  28. M. A. Fernández-Granero, D. Sánchez-Morillo, A. León-Jiménez, and L. F. Crespo, “Automatic prediction of chronic obstructive pulmonary disease exacerbations through home telemonitoring of symptoms,” Biomed Mater Eng., vol. 24, no. 6, pp. 3825–3832, 2014. View at: Google Scholar
  29. D. Sanchez-Morillo, M. A. Fernandez-Granero, and A. L. Jiménez, “Detecting COPD exacerbations early using daily telemonitoring of symptoms and k-means clustering: a pilot study,” Med Biol Eng Comput., vol. 53, no. 5, pp. 441–451, 2015. View at: Google Scholar
  30. H. Pinnock, J. Hanley, L. McCloughan et al., “Effectiveness of telemonitoring integrated into existing clinical services on hospital admission for exacerbation of chronic obstructive pulmonary disease: researcher blind, multicentre, randomised controlled trial,” BMJ, vol. 347:f6070, 2013. View at: Google Scholar
  31. A. Steventon, M. Bardsley, J. Billings et al., “Effect of telehealth on use of secondary care and mortality: findings from the Whole System Demonstrator cluster randomised trial,” BMJ, vol. 344:e3874, 2012. View at: Google Scholar

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