Low-Frequency Pulsed Electromagnetic Field Is Able to Modulate miRNAs in an Experimental Cell Model of Alzheimer’s Disease

Table 1

miRNAs studied and some of their targets that are involved in AD-related pathways.

ID	miRNA	Sequence	Target
MIMAT0000104	hsa-miR-107	50-agcagcauuguacagggcuauca-72	PLAG1, BACE1, CDK6, GRN, DAPK 1, PTEN,; NOTCH 2, NFIA, SERBP1
MIMAT0000765	hsa-miR-335-5p	16-ucaagagcaauaacgaaaaaugu-38	TNC, RASA1, IGFR1, SP1, APBB2
MIMAT0000083	hsa-miR-26b-5p	12-uucaaguaauucaggauaggu-32	SLC17A6, (DNP1/vGLUT2)

Note. PLAG1: pleiomorphic adenoma gene 1; BACE1: beta-site APP-cleaving enzyme 1; CDK6: cyclin-dependent kinase 6; GRN: granulin; DAPK 1: death-associated protein kinase 1; PTEN: phosphatase and tensin homolog; NOTCH 2: Notch 2; NFIA: nuclear factor I/A; SERBP1: SERPINE1 mRNA-binding protein 1; TNC: tenascin C; RASA1: RAS p21 protein activator (GTPase-activating protein) 1; IGFR1: insulin-like growth factor 1 receptor; SP1: Sp1 transcription factor; APBB2: Aβ precursor protein binding family B member 2; SLC17A6 (DNP1/vGLUT₂): solute carrier family 17 member 6 (vesicular glutamate transporter).