Predicting Interactions between Virus and Host Proteins Using Repeat Patterns and Composition of Amino Acids

Table 7

Results of independent testing our SVM on PPIs of new hosts with viruses.

Host	Sn (%)	Sp (%)	Acc (%)	PPV (%)	NPV (%)	MCC	AUC
Mus musculus	85.86	61.78	73.82	69.20	81.38	0.491	0.887
Bos taurus	98.40	27.20	62.80	57.48	94.44	0.365	0.926
Rattus norvegicus	91.86	27.90	59.88	56.03	77.42	0.257	0.828
Sus scrofa	100.00	5.26	52.63	51.35	100.00	0.164	0.952
Escherichia coli K-12	94.87	91.03	92.95	91.36	94.67	0.860	0.959
Average	92.02	54.23	73.13	67.80	86.86	0.501	0.911

Sn: sensitivity, Sp: specificity, Acc: accuracy, PPV: positive predictive value, NPV: negative predictive value, MCC: Matthews correlation coefficient, and AUC: the area under the ROC curve.