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Journal of Healthcare Engineering
Volume 2018, Article ID 4581272, 10 pages
Research Article

ANN and Fuzzy Logic Based Model to Evaluate Huntington Disease Symptoms

1Department of Multimedia Engineering, Kaunas University of Technology, Studentų 50, Kaunas, Lithuania
2Center of Real Time Computing Systems, Kaunas University of Technology, K. Baršausko 59, Kaunas, Lithuania
3Department of Software Engineering, Kaunas University of Technology, Studentų 50, Kaunas, Lithuania

Correspondence should be addressed to Andrius Lauraitis; tl.utk@sitiarual.suirdna

Received 28 September 2017; Accepted 24 January 2018; Published 11 March 2018

Academic Editor: Terry K.K. Koo

Copyright © 2018 Andrius Lauraitis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


We introduce an approach to predict deterioration of reaction state for people having neurological movement disorders such as hand tremors and nonvoluntary movements. These involuntary motor features are closely related to the symptoms occurring in patients suffering from Huntington’s disease (HD). We propose a hybrid (neurofuzzy) model that combines an artificial neural network (ANN) to predict the functional capacity level (FCL) of a person and a fuzzy logic system (FLS) to determine a stage of reaction. We analyzed our own dataset of 3032 records collected from 20 test subjects (both healthy and HD patients) using smart phones or tablets by asking a patient to locate circular objects on the device’s screen. We describe the preparation and labelling of data for the neural network, selection of training algorithms, modelling of the fuzzy logic controller, and construction and implementation of the hybrid model. The feed-forward backpropagation (FFBP) neural network achieved the regression R value of 0.98 and mean squared error (MSE) values of 0.08, while the FLS provides a final evaluation of subject’s reaction condition in terms of FCL.