Comparative Study on Automated Cell Nuclei Segmentation Methods for Cytology Pleural Effusion Images

Algorithm 6

: Minimum error thresholding method.

(1)	Compute the histogram that considers the mixture of two normal distributions having respective mean and variance, and respective proportions
(2)	Set the trial threshold value T for modeling the two resulting pixel populations
(3)	Model the two populations using the normal distribution
(4)	Set different levels as the threshold value
(5)	Compute the fitting criterion for each threshold value
(6)	Select the threshold value which minimizes the fitting criterion as the optimal threshold.