The Cell Research Trends of Asthma: A Stem Frequency Analysis of the Literature

Table 1

Top 50 stems of three decades.

Ranking	1st decade		2nd decade		3rd decade
	Stem	Frequency	Stem	Frequency	Stem	Frequency
1	eosinophil	147	inflamm	545	inflamm	1153
2	activ	115	express	425	respons	552
3	respons	113	eosinophil	358	express	537
4	inflamm	102	receptor	351	t	526
5	t	90	activ	341	activ	525
6	express	84	respons	339	receptor	508
7	bronchoalveolar	80	t	326	mice	476
8	role	76	role	321	role	429
9	lavag	75	induc	298	epitheli	422
10	mast	72	mast	232	induc	410
11	lymphocyt	71	smooth	229	muscl	406
12	atop	67	muscl	228	smooth	401
13	cytokin	61	epitheli	228	inhibit	401
14	receptor	60	cytokin	211	immun	336
15	releas	59	product	207	mous	333
16	induc	58	inhibit	205	murin	330
17	inhibit	55	allergen	200	mast	328
18	allergen	54	atop	177	eosinophil	294
19	product	53	protein	171	remodel	290
20	epitheli	53	sputum	168	signal	257
21	inhal	50	gene	166	protein	250
22	adhes	49	murin	160	children	245
23	mediat	47	mice	158	cytokin	244
24	inflammatori	46	pulmonari	148	inflammatori	235
25	children	45	inflammatori	146	suppress	234
26	histamin	43	hyperrespons	144	hyperrespons	232
27	muscl	41	children	136	pulmonari	230
28	leukotrien	40	inhal	136	gene	226
29	antigen	40	th2	118	product	224
30	smooth	40	remodel	118	th2	215
31	fluid	38	inhibitor	118	modul	213
32	sodium	38	mechan	116	dendrit	210
33	ige	37	develop	116	develop	207
34	peripher	34	rat	115	allergen	196
35	macrophag	34	allergeninduc	114	attenu	195
36	pulmonari	33	immun	113	pathway	190
37	vitro	32	lymphocyt	110	differenti	190
38	mechan	32	infect	106	target	185
39	select	31	sensit	102	novel	183
40	protein	30	novel	102	infect	177
41	therapi	28	mediat	100	mediat	176
42	glucocorticoid	28	peripher	100	regulatori	174
43	bronchoconstrict	28	signal	100	type	164
44	guinea	28	leukotrien	98	sever	164
45	chang	28	allergi	97	rat	164
46	pig	28	growth	97	promot	161
47	tcell	27	chemokin	96	inhibitor	156
48	hyperrespons	27	modul	93	allergi	156
49	immun	27	mous	93	mechan	151
50	modul	27	kinas	93	potenti	150