Research Article

Blood Glucose Level Prediction for Diabetics Based on Nutrition and Insulin Administration Logs Using Personalized Mathematical Models

Table 1

Glucose control model parameters (kgBW = body weight in kilograms).

NameDescriptionUnitValue

Rate of glucose uptake by insulin-dependent tissues3.1110−5
Net balance between hepatic glucose output and insulin-independent zero-order glucose uptake by brain0.003
Apparent distribution volume for glucose0.187
Apparent first-order disappearance rate constant for insulin1.21110−2
Maximal rate of second-phase insulin release0.1
Apparent distribution volume for insulin0.236
Apparent delay with which the pancreas varies secondary insulin release in response to varying plasma glucose concentrations24
Time-to-maximum insulin absorptionInsulin product dependent
The glycaemia at which the insulin release is half of its maximal rate9
The progressivity with which the pancreas reacts to circulating glucose concentrations3.205

Optimized values from [27].