Cloud-Based Brain Magnetic Resonance Image Segmentation and Parcellation System for Individualized Prediction of Cognitive Worsening

Table 2

Demographics and characteristics of the test dataset (MATC database).

Suspected diagnosis at baseline	N	Age	Sex (men/women)	MMSE at baseline	MMSE after 2 years	MMSE decline in 2 years	Number of patients with substantial worsening
AD	7	73.7 ± 11.0	4/1	21.9 ± 4.5	16.9 ± 8.0	−5.0 ± 5.8	4
MCI	3	82.5 ± 2.9	1/2	29.0 ± 0.8	26.3 ± 3.9	−2.7 ± 4.6	1
Others	7	69.8 ± 10.1	3/4	23.1 ± 7.0	20.6 ± 10.1	−2.6 ± 3.8	2
Total	17	73.7 ± 10.7	8/9	23.6 ± 6.0	20.0 ± 9.1	−3.6 ± 5.0	7

Others: mixed dementia, 2; vascular dementia, 1; frontotemporal dementia, 2; nonspecific cognitive disorder with depression, 2. ^∗Substantial worsening: MMSE declines ≤ −4 within two years.