Research Article

Wnt/β-Catenin, Carbohydrate Metabolism, and PI3K-Akt Signaling Pathway-Related Genes as Potential Cancer Predictors

Table 5

Performance of candidate pathway-related genes in cancer prediction.

ClassifiersPathway-related genes
WntCarbohydrate metabolismPI3K-Akt
COAD (%)BRCA (%)STAD (%)COAD (%)BRCA (%)STAD (%)COAD (%)BRCA (%)STAD (%)

SVM99.4999.4998.8499.4999.3999.1399.4999.4899.43
RF99.4999.2698.0499.2699.1696.8898.7999.4196.78
DT89.4592.5678.5199.3991.2474.6594.5193.3476.85
KNN99.4298.8593.5497.8399.4493.2797.8199.4594.71

Note. Tumor samples in the positive group versus the normal samples. COAD, colorectal cancer; BRCA, breast cancer; STAD, gastric cancer.