Research Article

[Retracted] RNF12 Promotes Glioblastoma Malignant Proliferation via Destructing RB1 and Regulating MAPK Pathway

Figure 5

RNF12 function in vivo. (a, b) Glioblastoma cells infected with RNF12-targeting shRNA or control shRNA. Representative pictures of subcutaneously implanted tumours (a) and tumour volume quantification (b). (c) Ki67, RNF12, and RB1 expression in xenografted tumour sections as shown by IHC. (d) A model showing how RNF12 controls the MAPK pathway and facilitates RB1 degradation. Three separate tests yielded comparable findings, and 1 sample result was displayed. The data are provided as mean standard deviation. .
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