Research Article
An Animated Functional Data Analysis Interface to Cluster Rapid Lung Function Decline and Enhance Center-Level Care in Cystic Fibrosis
Table 1
Features of rapid lung function decline summarized by primary care center
.
| | Features | Center type | | Small (<30) | Medium (30–150) | Large (>150) |
| | Center characteristics | | | | | No. of centers, n (%) | 78 (31.6%) | 133 (53.8%) | 36 (14.6%) | | No. of patients per center | 13.3 (8.1) | 72.7 (31.0) | 213.3 (60.5) | | No. of patients across centers | 1036 (5.6%) | 9674 (52.6%) | 7677 (41.8%) | | Patients within centers | | | | | Age at baseline, years | 13.5 (2.9)1 | 10.0 (1.8)2 | 8.6 (0.5)3 | | FEV1 at baseline, % predicted | 75.7 (13.9)1 | 82.9 (6.3)2 | 85.6 (5.2)3 | | Trajectories | | | | | FPCA | | | | | FPC1 score | 5.3 (10.9)1 | 2.3 (5.7)2 | 1.1 (5.3)3 | | Decline types by center, % | | | | | Early | 17.7 (17.1)1 | 24.0 (20.7)2 | 25.7 (22.7)3 | | Middle | 49.9 (9.7)NS | 49.8 (7.6)NS | 49.7 (9.9)NS | | Late | 32.4 (9.1)1 | 26.2 (6.6)2 | 24.6 (8.2)3 | | Peak decline | | | | | Extent, % predicted/year | −5.8 (1.3)1 | −6.5 (0.7)2 | −6.4 (0.6)3 | | Age of occurrence, years | 15.6 (2.2)1 | 15.1 (0.8)2 | 15.0 (0.5)3 |
|
|
