Text Mining-Based Drug Discovery in Osteoarthritis

Table 1

Lists of primer sequences used for quantitative real-time PCR.

Genes	Sequences
	Forward	Reverse
PTGS2	CCGAGGTGTATGTATGAGTG	GGGAGGGAGAAATTAATGGG
NLRP3	CACAGTCTAGTTGGGAAGAC	GAGACCATGTCTTCCATCAC
MMP13	CTTCCTCTTCTTGAGCTGG	GCAAGATACTCTACCTCTGC
MMP9	ATGTCTAAGGAGGGGAGATC	CTCAAACTCCTGAGCTTCAG
IL1RN	CTGGTATGTTCCTGTGGAAG	GGATAGGAGGCAGGACTAAT
CCL2	GTAATCAAAGAGAGGGTGGG	CTCATTACCTCTGCAGAGTC
CXCL8	CAAGCTTCTAGGACAAGAGC	CTTACCTTCACACAGAGCTG
TNFRSF1B	GGGCTGTCAGACTAGAATTG	CAGAGTATATGGCATGACCC
TNF	GAAGACACTCAGGGAAAGAG	TGATTAGAGAGAGGTCCCTG
CASP3	CAGGCAGAGGGATCTTTATG	CACTAGGTATGAAGGTCAGC
IL10	GCTTCTTAATCCCTGGGATC	CTCAGTCCTGGTCTTCTTTC
CD40	CCAAAGGTCTCATAGCTAGC	GTTCTCACTCCCCATAGTTC
MAPK8	GAGGTCAGATGCTCTAAGTG	CTATATTCCAGGCTAGGTGG
STAT3	CTGAAAGACTTCATGGGAGG	CCTCACTTCCCAAGTTAGAC
IL6	CGTCCGTAGTTTCCTTCTAG	AGGGGGAGAATACTACTCAC
NGF	CTCTTGTTGAAGGGGGATAG	CTCTGAGGTGCTCCTATACT
TP53	GATGAGTCCTCTCTGAGTCA	GTCCTAACATCCCCATCATC
RELA	CTATGAAGTAGCCGCTACAG	GAAGTGATTAGGGACCCATC
BCL2L1	TAGACCCAGACCTTCGTAAG	GAAGGGAGAGAAAGAGCTTC
VEGFA	CAGTGCTAGGAGGAATTTCC	CAGTGATCATCCTTTCCCTG
NOTCH1	GGCGAGAATTATCTGTCCTC	GGATCAATTACTCAAGCCCC
HMGB1	CAGGAGATCAGCAGAGATTG	CTGGGACCAGGATATGTAGA