Efficacy of Whole-Body Vibration Training on Brain-Derived Neurotrophic Factor, Clinical and Functional Outcomes, and Quality of Life in Women with Fibromyalgia Syndrome: A Randomized Controlled Trial

Table 4

Biomarker levels and clinical and functional outcomes at baseline.

Outcome	CG (n = 15)	IG (n = 17)	value
Biomarker(ng/mL)
BDNF	2.39 (1.82–2.96)	2.35 (1.59–3.11)	0.922
Functional outcomes
6MWT, m	427.27 (398.96–455.58)	447.35 (418.78–476.74)	0.292
STS, rep.	8.27 (6.71–9.93)	8.00 (6.48–9.52)	0.976
Clinical outcomes
FIQ, score	66.68 (59.27–74.09)	72.53 (64.21–80.85)	0.277
Pain, VAS	5.77 (4.55–6.99)	7.14 (6.24–8.04)	0.081
PSQI, score	13.33 (11.61–15.05)	12.18 (9.78–14.58)	0.422
BDI, score	25.20 (19.34–31.06)	21.65 (16.43–26.87)	0.341

Values are means (95% confidence interval). CG: control group (n = 15). IG: intervention group (n = 17). BDNF, brain-derived neurotrophic factor; 6MWT, six-minute walk test; STS, sit-to-stand test; rep: repetition; FIQ, Fibromyalgia Impact Questionnaire; VAS, visual analogue scale; PSQI, Pittsburgh Sleep Quality Index; BDI, Beck Depression Inventory. p value: unpaired t-test (all variables showed normal distribution).