Table of Contents
Journal of Hormones
Volume 2014 (2014), Article ID 750401, 4 pages
http://dx.doi.org/10.1155/2014/750401
Research Article

Utility of Intraoperative Parathormone Assay as an Index to Successful Parathyroidectomy

Fortis Hospitals, Mulund, Mumbai 400080, India

Received 15 December 2013; Revised 5 May 2014; Accepted 7 May 2014; Published 19 May 2014

Academic Editor: Tullio Florio

Copyright © 2014 Ranjeetha Shenoy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. Surgery is the definitive treatment for primary hyperparathyroidism (PHP). Focused approaches for excision of single gland pathology are gaining popularity. Preoperative parathyroid localization and intraoperative parathormone (IOPTH) assay are essential components of successful parathyroidectomy using focused approach. Objective. To evaluate the efficacy of IOPTH in patients undergoing surgery for PHP. Methods. Retrospective review of twelve patients who underwent surgery for PHP at tertiary corporate hospital in Mumbai, India, between January 2009 and December 2012. Results. IOPTH had true results in 10 patients (83%) and led to unnecessary further exploration in 1 patient (8%). The concordance rate between ultrasonogram, sestamibi, and IOPTH was 66%. The mean decay of IOPTH was 65%, and all patients were normocalcemic at the end of six months. Conclusion. IOPTH is a useful adjunct to predict successful removal of the involved gland.