Spectroscopic Characterization, In Vitro Cytotoxicity, and Antioxidant Activity of Mixed Ligand Palladium(II) Chloride Complexes Bearing Nucleobases

Table 3

¹H-NMR data of the complexes and the free nucleobase ligands.

Complex	H-NMR^a
cis-[PdCl2(cyt)(gua)]	5.56 (1H, s, H-5(cyt)), 7.40 (1H, s, H-6(cyt)), 7.70 (s, NH2(cyt)), 11.27 (1H, s, H-1(cyt)), 5.95 (s, NH2(gua)), 8.83 (1H, s, H-8(gua)), 9.40 (1H, s, H-9(gua)), 12.03 (1H, s, H-1(gua)).
cis-[PdCl2(cyt)(ad)]	5.90 (1H, s, H-5(cyt)), 7.71 (s, NH2(cyt)), 8.13 (1H, s, H-6(cyt)), 2.01 (1H, s, H-1(cyt)), 7.70 (s, NH2(ad)), 8.38 (1H, s, H-2(ad)), 9.37 (1H, s, H-8(ad)), 12.00 (1H, s, H-9(ad))
cis-[PdCl2(ad)(gua)]	8.33 (s, NH2(ad)), 8.78 (1H, s, H-8(ad)), 9.20 (1H, s, H-2(ad)), 13.45 (1H, s, H-9(ad)), 6.63 (s, NH2(gua)), 8.29 (1H, s, H-8(gua)), 11.17 (1H, s, H-9(gua)), 14.06 (1H, s, H-1(gua))
Cytosine	5.56 (1H, s, H-5), 7.06 (s, NH2), 7.32 (1H, s, H-6), 10.56 (1H, s, H-9)
Adenine	7.11 (s, NH2), 8.10 (2H, s, H-2 and H-8), 12.86 (1H, s, H-9)
Guanine	5.57 (s, NH2), 7.08 (1H, s, H-8), 10.55 (1H, s, H-9)

a25°C in DMSO-d₆  δ [ppm].