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Developmental Immunology
Volume 1, Issue 1, Pages 53-57
http://dx.doi.org/10.1155/1990/56014

Immunoglobulin λ Gene Rearrangement Can Precede κ Gene Rearrangement

Department of Microbiology and Immulology, University of California, San Francisco, California 94143-0414, USA

Received 15 October 1989; Accepted 27 October 1989

Copyright © 1990 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [23 citations]

The following is the list of published articles that have cited the current article.

  • Ge Wu, and Da Ramsden, “Mouse Kappa-Light-Chain Recombination Signal Sequences Mediate Recombination More Frequently Than Do Those Of Lambda-Light Chain,” Proceedings Of The National Academy Of Sciences Of The United States Of Ame, vol. 88, no. 23, pp. 10721–10725, 1991. View at Publisher · View at Google Scholar
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  • Gadi Spira, Ruirong Yuan, Melia Paizi, Margrit Weisendal, and Arturo Casadevall, “ Short Communication: Simultaneous Expression of k and λ Light Chains in a Murine IgG 3 Anti- Cryptococcus neoformans Hybridoma Cell Line ,” Hybridoma, vol. 13, no. 6, pp. 531–535, 1994. View at Publisher · View at Google Scholar
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  • A Lanzavecchia, E Padovan, and C Giachino, “Kappa(+)Lambda(+) Dual Receptor B-Cells Are Present In The Human Peripheral Repertoire,” Journal Of Experimental Medicine, vol. 181, no. 3, pp. 1245–1250, 1995. View at Publisher · View at Google Scholar
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  • S Takeda, H Arakawa, and T Shimizu, “Re-evaluation of the probabilities for productive rearrangements on the kappa and lambda loci,” International Immunology, vol. 8, no. 1, pp. 91–99, 1996. View at Publisher · View at Google Scholar
  • James R. Gorman, and Frederick W. Alt, “Regulation of Immunoglobulin Light Chain Isotype Expression,” Advances in Immunology Volume 69, vol. 69, pp. 113–181, 1998. View at Publisher · View at Google Scholar
  • Tamotsu Yamagami, Edwin ten Boekel, Christoph Schaniel, Jan Andersson, Antonius Rolink, and Fritz Melchers, “Four of Five RAG-Expressing JCκ−/− Small Pre-BII Cells Have No L Chain Gene Rearrangements,” Immunity, vol. 11, no. 3, pp. 309–316, 1999. View at Publisher · View at Google Scholar
  • Holger Engel, Antonius Rolink, and Siegfried Weiss, “B cells are programmed to activate κ and λ for rearrangement at consecutive developmental stages,” European Journal of Immunology, vol. 29, no. 7, pp. 2167–2176, 1999. View at Publisher · View at Google Scholar
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  • N. R. Ruetsch, G. C. Bosma, and M. J. Bosma, “Unexpected Rearrangement and Expression of the Immunoglobulin  1 Locus in Scid Mice,” Journal of Experimental Medicine, vol. 191, no. 11, pp. 1933–1944, 2000. View at Publisher · View at Google Scholar
  • José Luis Vela, Djemel Aït-Azzouzene, Bao Hoa Duong, Takayuki Ota, and David Nemazee, “Rearrangement of Mouse Immunoglobulin Kappa Deleting Element Recombining Sequence Promotes Immune Tolerance and Lambda B Cell Production,” Immunity, vol. 28, no. 2, pp. 161–170, 2008. View at Publisher · View at Google Scholar
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