Methotrexate and Cyclosporine Treatments Modify the Activities of Dipeptidyl Peptidase IV and Prolyl Oligopeptidase in Murine Macrophages

<table>Percentual
activity of soluble and membrane-bound dipeptidyl peptidase IV (DPPIV) and
prolyl oligopeptidase (POP) activities in resident and thioglycollate-elicited
murine macrophages from cyclosporine-treated in relation to the respective
control (100%). Values are means ± SEM from 5 animals (assays made in
triplicate). <svg height="13.425" id="M94" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 10.2 13.425" width="10.2" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,13.425)">
<g transform="translate(72,-61.26)">
<text transform="matrix(1,0,0,-1,-71.95,63.6)">
<tspan style="font-size: 12.50px; " x="0" y="0">??</tspan>
</text>
</g>
</g>
</svg> in comparison to control (unpaired
two-sided Student's <i>t</i>-test).</table>

Journal of Immunology Research

fig4

Figure 4

Figure 4: Methotrexate and Cyclosporine Treatments Modify the Activities of Dipeptidyl Peptidase IV and Prolyl Oligopeptidase in Murine Macrophages 