T Cell-Tumor Interaction Directs the Development of Immunotherapies in Head and Neck Cancer

Table 2

Examples for studies targeting CSC with CTL.

Target	Tissue	Ref
Dendritic cells loaded with CSC as antigen source	glioblastoma	[72]
CD8 defined ALDH1-specific T-cell epitope	HNSCC	[73]
Vaccination with murine prostate stem cell antigen encoding cDNA	Murine prostate cancer	[74]
Dendritic cells loaded with neurospheres from brain glioma cells	Murine glioma	[75]
Identification of 2 CD8 defined prostate stem cell antigen-specific T-cell epitopes	Prostate cancer	[76]
Vaccination with defined human embryonic stem cells (hESCs) or induced pluripotent stem (iPS) cells	Colon cancer	[5]
CD8 defined SOX2-specific T-cell epitopes	Glioma	[77, 78]