Clinical Study

Clinical Characteristics of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in North Indian Population of HIV/AIDS Patients Receiving HAART

Table 7

Comparison of characteristics between HIV-TB patients without and with TB-IRIS and HIV patients with ART associated TB.

No TB-IRISTB-IRISART-associated TB
( )( )( )

Age (yrs)37 ± 1031 ± 735 ± 15
Sex (% male)808050
BMI (kg/m2)19 ± 518 ± 319.4 ± 4
ATT-ART (days)32 (21–70)20 (18–27)
ART-IRIS (days)73 (6–84)37 (7–88)
CD4 (cells/ l)136 (70–225.75)167 (118–193)132 (57.25–182.75)
Increase in CD4 (cells/ l)89 (32.25–144.75)229 (61–283)161 (129–316)
Increase in CD4 (%)57.6 (24–181)119 (63.5–207)160 (72–369)
VL (log10 copies/ml)5.21 (4.76–5.65)5.49 (5.18–5.63)5.28 (4.95–5.51)
Decrease in VL (log10 copies/ml)5.19 (4.76–5.63)5.49 (5.18–5.63)5.13 (4.87–5.39)
Decrease in VL (%)99.58 (98.85–99.9)99.93 (99.91–99.97)99.91 (99.84–99.93)

BMI: body mass index; ATT: antituberculosis treatment; ART: antiretroviral treatment; VL: viral load
Age and BMI are presented as mean ± SD; gender as % of male and ATT-ART gap, ART-IRIS gap, CD4 cell counts and viral load as median and IQR.