Research Article

Phenotype and Function of CD25-Expressing B Lymphocytes Isolated from Human Umbilical Cord Blood

Table 1

Comparison of homing receptor and activation marker expression between CD20+CD25+ or CD20+CD25- cells isolated from human cord blood or from adult peripheral blood.

Cord bloodAdult peripheral blood value
CD20+CD25+CD20+CD25CD20+CD25+CD20+CD25

CCR4 0.0006
0.0001
0.001§
CCR7 0.0001
0.003
0.006
CCR9 0.002
0.005
0.03
CCR10 0.003
0.001
n.s
L-selectin 0.006
0.003
0.04
CD80 0.04
0.0006
0.03
CD86 0.02
n.s
0.05

Values are expressed as frequency of expression in %  ± SEM.
Comparison between cord blood CD20+CD25+ and CD20+CD25-.
Comparison between peripheral adult blood CD20+CD25+ and CD20+CD25- .
§ Comparison between cord blood CD20+CD25+ and peripheral adult blood CD20+CD25.