Immunology and Immunodiagnosis of Cystic Echinococcosis: An Update

Table 1

Characteristics of assays using different antigens from E. granulosus developed after 2003 for immunodiagnosis of cystic echinococcosis.

Number of subjects tested			Antigen	Assay method	Sensitivity (%)	Specificity (%)	Ig isotype	Refs.
CE	Healthy controls	Other diseases
44	—	43	8 kDa	WB	47.7	51.2	IgG	[67]
44	—	43	16 kDa	WB	45.5	67.4	IgG	[67]
44	—	43	24 kDa	WB	68.2	62.8	IgG	[67]
36	36	—	AgB	ELISA	91.7	97.2	IgG	[68]
102	95	68	rAgB1	ELISA	88.2	80.9	IgG	[69]
102	95	68	rAgB2	ELISA	91.2	93	IgG	[69]
875	5	739	AgB	Dot-WB	68.4	93.4	IgG	[70]
857	5	739	AgB	ELISA	57.4	93.4	IgG	[70]
324	70	500	AB	WB	86.4	92	IgG	[71]
155	110	58	?	ELISA	73.6	99.1	IgE	[72]
875	5	739	AgB	Dot-WB	68.4	93.4	IgG	[70]
857	5	739	AgB	ELISA	57.4	93.4	IgG	[70]
324	70	500	AB	WB	86.4	92	IgG	[71]
155	110	58	?	ELISA	73.6	99.1	IgE	[72]
155	110	58	?	ELISA	90.3	90.9	IgG	[72]
155	110	58	HCF	WB	90.1	94.5	IgG	[72]
324	70	500	EpC1	WB	88.7	95.6	IgG	[71]
95	37	—	HSP20		64		IgG1,4	[73]
97	37	58	Eg19	WB	10	100	IgG	[74]
102	95	68	E14t	ELISA	35.3	91.7	IgG	[69]
102	95	68	C317	ELISA	58.8	80.9	IgG	[69]
60	—	—	P5	WB	97	1	1	[75]

ELISA: enzyme-linked immunosorbent assay; WB: western blotting; dELISA: dot enzyme-linked immunosorbent assay.