The Development of Severe Neonatal Alloimmune Thrombocytopenia due to Anti-HPA-1a Antibodies Is Correlated to Maternal ABO Genotypes
The maternal ABO type distribution in the pregnancies compared to the severity of NAIT.
|Relative risk of NAIT was 0.67 (95% CI 0.48–0.94) in neonates born of women with blood group O versus blood group A. |
Relative risk of severe NAIT was 0.43 (95% CI 0.25–0.75) in neonates born of women with blood group O versus blood group A.
†Chi-square test (two-sided) for frequencies of NAIT and severe NAIT in blood group O compared to blood group A.