The Development of Severe Neonatal Alloimmune Thrombocytopenia due to Anti-HPA-1a Antibodies Is Correlated to Maternal ABO Genotypes

Table 2

Platelet counts in the newborns with NAIT.

Maternal ABO types		N *	Median platelet count	Mean platelet count (95% CI)	𝑃 value with Bonferroni correction
Blood group O	Genotype O01/O01	9	86	83.2 (56.9–109.6)
	Genotypes O01/O02 and O02/O02	17	21	43.7 (22.7–64.7)	0.043^†
Blood group A		47	31	46.1 (35.0–57.2)	0.028^†

*Total number of pregnancies resulting in a newborn with NAIT (platelet count ≤150) was 83. DNA for genotyping was available for 68 women with blood group O or A, and they had altogether 73 HPA-1-incompatible pregnancies.
^† Comparison with platelet counts in children born of women with the genotype O01/O01.