Review Article
Macroprolactinemia: Diagnostic, Clinical, and Pathogenic Significance
Table 1
Advantage and disadvantage of methods for the diagnosis of macroprolactinemia.
| ā | Advantage | Disadvantage |
| Polyethylene glycol (PEG) | Simple and inexpensive | Not highly specific | Screening for macroprolactinemia |
| Gel chromatography | Accurate Confirming macroprolactinemia | Time consuming and expensive |
| Protein A/G | Identifying IgG-bound PRL (common cause of macroprolactin) | Expensive |
|
125I-PRL binding | Identifying anti-PRL autoantibodies (common cause of IgG-bound PRL) | Time consuming and hazardous Needs radio isotope facilities |
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