Research Article

Herpes Simplex Virus-2 Glycoprotein Interaction with HVEM Influences Virus-Specific Recall Cellular Responses at the Mucosa

Figure 4

CD4+ T cell frequencies do not differ in draining lymph nodes (a) or vaginal mucosa (b) among lymphocytes isolated from groups of mice primed with viruses that can (HSV-2/gD-βgal, left, open circles) or cannot (HSV-2/gD-Δ7-15-βgal, right, filled triangles) engage HVEM. Symbols show data from individual mice, with the horizontal line designating the mean for each experimental group. Data are pooled from three independent experiments with 3-4 mice per group.
284104.fig.004a
(a)
284104.fig.004b
(b)