Enhanced HMGB1 Expression May Contribute to Th17 Cells Activation in Rheumatoid Arthritis

Figure 5

The number of IL-17-expressed CD4⁺T cell stimulated by HMGB 1. The conditions were designed as before. The cells were collected; before 6h, 1 μL monosion, 5 μL 10 ng/mL PMA, and 1 μL 1 Mm/mL inon were added. (a) Presents medium control, stimulated for 12 h; (b) Presents independence protein, stimulated for 12 h; (c) Presents LPS, stimulated for 12 h; (d) Presents 100 ng/mL HMGB 1 stimulated for 12 h; (e) Presents 100 ng/mL HMGB 1 stimulated for 24 h; (f) Presents 1000 ng/mL HMGB 1 stimulated for 12 h.

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(b)

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