Pulmonary Immune-Compartment-Specific Interferon Gamma Responses in HIV-Infected Individuals with Active Tuberculosis (TB) in an Area of High TB Prevalence

Figure 6

ROC curve analysis of diagnostic accuracy of sputum PPD-induced IFNγ. The sensitivity and specificity for discriminating active TB from non-active TB, at a diagnostic threshold of PPD-induced gamma interferon production by 1.2% of total lymphocytes (larger red point), were 78% and 70%, respectively, yielding positive and negative predictive values of 70% and 78%.