Journal of Immunology Research / 2012 / Article / Fig 1

Research Article

Characterization of Outer Membrane Vesicles from Brucella melitensis and Protection Induced in Mice

Figure 1

Electron microscopy of OMVs from smooth B. melitensis M16 and rough B. melitensis VTRM1. Negative stain of OMVs released from surface B. melitensis VTRM1 (a) and B. melitensis 16 M (b); negative stain of OMV purified by differential centrifugation from both strains; B. melitensis VTRM1 (c) and B. melitensis 16 M (d). The arrows point to the apparent shedding of the OMVs from the cell surface in (a) and (b); while the arrows in (c) and (d) point to spherical OMVs purified from both strains. The bars correspond to 100 nm.

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