Lactococcus lactis NCC 2287 Alleviates Food Allergic Manifestations in Sensitized Mice by Reducing IL-13 Expression Specifically in the Ileum
Figure 3
Decreased IL-13 production from restimulated MLN cells in mice administered L. lactis NCC 2287 in the management phase. IL-4 (a), IL-5 (b), IL-10 (c), and IL-13 (d) levels in the supernatants of MLN cells restimulated ex vivo with OVA. Positive control group secreted increased levels of Th-2 cytokines. MLN cells from mice administered L. lactis NCC 2287 during the prevention phase exhibited similar levels of Th-2 cytokines as the positive control group. MLN cells of mice administered L. lactis NCC 2287 during the management phase produced decreased levels of IL-13 cytokine levels but not IL-4, IL-5, or IL-10.
