Clinical Usefulness of the Serological Gastric Biopsy for the Diagnosis of Chronic Autoimmune Gastritis

Table 1

Analytic data of the four serological markers in relation to histological diagnosis.

Histological diagnosis	Number of patients	Age (years) (mean ± SD)	PCA (U/mL) (mean ± SD); (cutoff 30)	IFA (U/mL) (mean ± SD); (cutoff 20)	Gastrin (pg/mL) (mean ± SD); (cutoff 115)	Anti-Hp positivity; (%)
Group 1: autoimmune gastritis	30	53.5±20.0	65±29	12±2	𝟏𝟎𝟒𝟖±956	26.0
Group 2: gastric atrophy	14	70.4±16.5 *	59±23	67±8 *	𝟏𝟓𝟐𝟑±713 *	0*
Group 3: non-specific lymphocytic gastritis	18	45.7±12.0	52±17	5±4	38±8 *	21.1
Group 4: multifocal atrophic gastritis	21	70.6±11.9 *	18±8 *	6±6	56±11 *	100*

PCA: anti-parietal-cell antibodies; IFA: anti-intrinsic-factor antibodies; anti-Hp: anti-Helicobacter  pylori antibodies; *statistical significance (𝑃<0.05).