Journal of Immunology Research / 2012 / Article / Tab 2

Review Article

Mesangial Cell-Specific Antibodies Are Central to the Pathogenesis of Lupus Nephritis

Table 2

Glomerular targets for anti-double-stranded (ds)-DNA antibodies [11, 12].

Molecules that directly cross-react with anti-dsDNA antibodiesCell type/glomerular matrix

Alpha-actininMesangial cells
Annexin A2Mesangial cells, epithelial cells
Ribosomal P proteinMesangial cells, endothelial cells
Alpha-enolaseMesangial cells, epithelial cells
LamininGlomerular matrix
FibronectinGlomerular matrix
CollagenGlomerular matrix
Heparan sulfateGlomerular matrix
Hyaluronic acidGlomerular matrix

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