Impact of the NK Cell Receptor LIR-1 (ILT-2/CD85j/LILRB1) on Cytotoxicity against Multiple Myeloma
NK-92 mediated killing of target cell lines is dependent on applied E : T ratio. CRA revealed a clearly E : T-dependent level of NK-92 mediated cytotoxicity. Results of CRA are represented as means of at least three independent experiments ± SD. Values in the table below are given as % specific lysis. AML cell line HL60 was almost resistant to NK-92 mediated killing. NK-92 cells were stimulated with 200 U/ml IL-2 the day before the assay.
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