Oral Tolerance Induced by Transfer of Food Antigens via Breast Milk of Allergic Mothers Prevents Offspring from Developing Allergic Symptoms in a Mouse Food Allergy Model
Figure 7
Effects of the maternal exposure to food antigens during lactation and the maternal allergic status on plasma OVA-specific IgG1 and IgA levels in offspring. We found OVA-specific IgG1 only in the plasma of naïve offspring breastfed by OVA-sensitized mothers, which implies that OVA-specific IgG1 transferred from mothers circulate in their offspring. Plasma OVA-specific IgA levels were undetectable in the four groups of offspring. Data are shown as the means and individual data points. N.D.: not detectable. *, **, n = 5–7.