Journal of Immunology Research / 2012 / Article / Fig 3

Research Article

Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production

Figure 3

Regulatory T cells accumulate in the airways of allergic but not tolerant mice. Time course of (a) CD4+CD25+Foxp3+ (Treg) and (b) CD4+CD25+Foxp3 (Teff) cells number in the BAL of allergic and tolerant mice. (c) Frequency and (d) number of CD4+CD25+ lung cells expressing or not Foxp3. Pooled cells from three mice recovered from BAL and lung were stained for CD4, CD25, and Foxp3 and gated in CD4-positive cells. Values in (a) and (b) represent the means ± SEM for groups of three mice and are representative of two experiments. The data in (c) show a representative experiment of two. Significant differences ** , *** are related to tolerant group.
721817.fig.003a
(a)
721817.fig.003b
(b)
721817.fig.003c
(c)
721817.fig.003d
(d)
721817.fig.003e
(e)

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.