Journal of Immunology Research / 2012 / Article / Tab 1 / Research Article
Automatic Reading of ANCA-Slides: Evaluation of the AKLIDES System Table 1 Interference of ANCA pattern recognition in sera containing ANA or AMA.
Visual score AKLIDES Concordance ANA homogenous 1/80 (
) 3 negative, 3 nuclear 3 negative, 3 P-ANCA 3/6 (50.0%) 1/320 (
) 2 negative, 5 nuclear 2 negative, 5 P-ANCA 2/7 (28.6%) 1/1280 (
) 4 nuclear, 3 P-ANCA 7 P-ANCA 3/7 (42.9%) ANA speckled (
) 2 negative, 2 nuclear, 1 atypic 2 negative, 2 P-ANCA, 1 ANA-dots 3/5 (60.0%) Atypical speckled (
) 1 negative, 3 P-ANCA 1 negative, 2 P-ANCA, 1 undetermined 3/4 (75.0%) Centromere (
) 3 nuclear, 1 atypic 4 ANA-dots 3/4 (75.0%) Nucleolar (
) 2 negative 2 negative 2/2 (100%) AMA (
) 1 negative, 2 P-ANCA, 4 negative, 3 P-ANCA, 1 C-ANCA, 4/11 (36.4%)
AMA: antimitochondrial antibodies; ANA: antinuclear antibodies; ANCA: antineutrophil cytoplasmic antibodies.
