Beneficial Effect of Bupleurum Polysaccharides on Autoimmune-Prone MRL-lpr Mice

Table 1

Effect of BPs on lymphadenopathy of MRL-lpr mice.

Weeksof age	lymphadenopathy score
	Model	BPs			Prednisone
		15 mg·kg^−1	30 mg·kg^−1	60 mg·kg^−1	5 mg·kg^−1
16	0 (0~1)	0.5 (0~1)	1 (0~1)	0 (0~1)	0 (0~0)
18	1 (0~2)	1.5 (0~2)	1 (0~2)	0 (0~2)	0 (0~1)
20	2 (0~3)	2 (0~3)	1.5 (0~3)	0 (0~3)^a	1 (0~2)
21	2 (1~3)	2 (0~3)	2 (0~3)	0 (0~3)^a	1 (0~2)^a
22	3 (2~3)	2 (0~3)	2 (0~3)	0 (0~3)^b	1 (0~2)^b
23	3 (2~3)	3 (0~3)	2.5 (0~3)	0 (0~3)^b	1 (0~3)^a
24	3 (2~3)	3 (0~3)	3 (0~3)	0 (0~3)^b	1.5 (0~3)^a

note: Data were expressed as median (minimum~maximum) (𝑛 = 6–8); ^a𝑃<0.05, ^b𝑃<0.01 compared with vehicle treated model group, tested by Mann-Whitney 𝑈 test.