PD-L1-Expressing Dendritic Cells Contribute to Viral Resistance during Acute HSV-1 Infection
Figure 1
HSV-1 viral load following anti-PD-L1, anti-PD-L2, or anti-PD-1 antibody treatment. C57BL/6 mice were infected with 1,000 PFU HSV-1/cornea. At days 2, 4, and 6 p.i. mice were administered neutralizing antibody to PD-L1, PD-L2, PD-1, or control IgG. The corneas (a) and TG (b) were harvested at 7 days p.i. and HSV-1 viral titers were assessed by plaque assay. This figure summarizes three experiments (). Each bar represents the mean ± SEM. * comparing the indicated group to the isotypic control antibody-treated group.
