Transfer of Maternal Immunity to Newborns of Diabetic Mothers

Table 2

Mean (±SD) immunoglobulin level in colostrum, maternal blood, and cord blood from normoglycemic and hyperglycemic women.

Parameter	Sample	Normoglycemic	Hyperglycemic	Statistical contrast
IgG (mg/dL)	Colostrum	120.8 ± 43.7	82.5 ± 27.7^†	Colostrum versus blood 𝐹=78.6; 𝑃=0.001
	Maternal blood	2014.6 ± 261.6*	1649.3 ± 207.8^*†	Normo- versus hyperglycemic 𝐹=16.7; 𝑃=0.0003
	Cord blood	1940.4 ± 327.4*	2570.9 ± 466.1^*#†
IgA (mg/dL)	Colostrum	417.8 ± 51.3	291.5 ± 90.3^†	Colostrum versus blood 𝐹=68.87; 𝑃=0.0004
	Maternal blood	55.4 ± 7.1*	43.0 ± 5.1*	Normo- versus hyperglycemic 𝐹=16.90; 𝑃=0.006
	Cord blood	24.4 ± 4.7^*#	22.5 ± 8.8^*#
IgM (mg/dL)	Colostrum	36.2 ± 10.5	36.2 ± 8.5	Colostrum versus blood 𝐹=15.39; 𝑃=0.005
	Maternal blood	52.8 ± 13.8	37.3 ± 6.9^†	Normo- versus hyperglycemic 𝐹=16.81; 𝑃=0.02061
	Cord blood	13.5 ± 5.3^*#	13.0 ± 7.7^*#

Within a same group (normo- or hyperglycemic), ∗indicates statistical differences between colostrum and blood and #indicates differences between maternal blood and cord blood immunoglobulin levels. †Indicates statistical differences in immunoglobulin levels between normo- and hyperglycemic women (in a row).