Tolerogenic versus Inflammatory Activity of Peripheral Blood Monocytes and Dendritic Cells Subpopulations in Systemic Lupus Erythematosus

Table 3

Frequency and absolute value of monocytes and peripheral blood dendritic cells in the three studied groups (HG, ASLE, and ISLE).

	HG	ASLE	ISLE
	(𝑛=30)	(𝑛=18)	(𝑛=25)
Frequency (%)
Monocytes	3.9 ± 0.97	3.02 ± 1.61	3.56 ± 1.32
CD14^−/lowCD16^+ DCs	0.54 ± 0.29	0.45 ± 0.30	0.55 ± 0.33
mDCs	0.29 ± 0.18*	0.21 ± 0.15**	0.29 ± 0.32
pDCs	0.10 ± 0.07*	0.02 ± 0.03	0.07 ± 0.07***
Absolute Value (cells/μL)
Monocytes	284,6 ± 84,2*	193,3 ± 97,5	228,4 ± 87,1
CD14^−/lowCD16^+ DCs	39,2 ± 23,2	28,1 ± 20	34,1 ± 19,1
mDCs	21,4 ± 15,1	13,9 ± 11,1	18,2 ± 14
pDCs	7.08 ± 5.16*	1.24 ± 1.28**	3.82 ± 3.51***

Note: results are expressed as mean ± standard deviation.
Statistically significant differences were considered when 𝑃<0.05 (Mann-Whitney 𝑈 test): *HG versus ASLE; **ASLE versus ISLE., ***HG versus ISLE.
HG: healthy control group.
ASLE: active disease group.
ISLE: inactive disease group.